For more than a decade, NASA has used saturation diving from the Aquarius underwater habitat as a real world environmental analog that bridges the gap between simulation and actual spaceflight. Presenter Karl Shreeves has been part of the NEEMO team since its inception in 2001, and presents a pictorial overview of NEEMO's use of high end dive gear, submersibles, high-fidelity mockups, cutting edge electronics and extensive topside support to explore issues related to orbital, lunar, Martian and asteroid human missions. Images all Courtesy of NASA/NEEMO